Junli Chen Selected Research

HMGN2 Protein (HMGN2)

12/2019	HMGN2 regulates non-tuberculous mycobacteria survival via modulation of M1 macrophage polarization.
1/2019	High-mobility group protein N2 induces autophagy by activating AMPK/ULK1 pathway and thereby boosts UPEC proliferation within bladder epithelial cells.
1/2018	Non-histone nuclear protein HMGN2 differently regulates the urothelium barrier function by altering expression of antimicrobial peptides and tight junction protein genes in UPEC J96-infected bladder epithelial cell monolayer.
1/2017	Nuclear protein HMGN2 attenuates pyocyanin-induced oxidative stress via Nrf2 signaling and inhibits Pseudomonas aeruginosa internalization in A549 cells.
9/2016	Knockdown of HMGN2 increases the internalization of Klebsiella pneumoniae by respiratory epithelial cells through the regulation of α5β1 integrin expression.

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Junli Chen Research Topics

Disease

8	Neoplasms (Cancer) 11/2021 - 10/2012
7	Infections 03/2021 - 09/2016
2	Death (Near-Death Experience) 01/2021 - 01/2020
2	Inflammation (Inflammations) 01/2020 - 01/2019
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 10/2017 - 10/2012
2	Breast Neoplasms (Breast Cancer) 09/2017 - 01/2016
2	Carcinogenesis 09/2017 - 06/2015
1	Liver Failure 01/2022
1	End Stage Liver Disease 01/2022
1	Hemophilia A (Haemophilia) 01/2022
1	COVID-19 01/2021
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2021
1	Chemical and Drug Induced Liver Injury 01/2021
1	Virus Diseases (Viral Diseases) 01/2020
1	Chronic Hepatitis C 01/2020
1	Bacterial Infections (Bacterial Infection) 01/2019
1	Vitamin D Deficiency 11/2018
1	Necrosis 11/2018
1	Thrombosis (Thrombus) 12/2017
1	Melanoma (Melanoma, Malignant) 12/2017
1	Lung Neoplasms (Lung Cancer) 09/2017
1	Communicable Diseases (Infectious Diseases) 01/2017
1	Persistent Infection 06/2016
1	Spinal Cord Injuries (Spinal Cord Injury) 05/2016
1	Memory Disorders (Memory Loss) 01/2016
1	Amyloidosis 01/2016
1	Alzheimer Disease (Alzheimer's Disease) 01/2016
1	Osteosarcoma (Osteogenic Sarcoma) 09/2015
1	Neoplasm Metastasis (Metastasis) 09/2015
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2014
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 05/2013
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2013

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2016
5	HMGN2 Protein (HMGN2)IBA 12/2019 - 09/2016
4	Pharmaceutical PreparationsIBA 01/2020 - 01/2014
4	Histone Deacetylase InhibitorsIBA 10/2017 - 10/2012
3	Amyloid (Amyloid Fibrils)IBA 12/2017 - 01/2016
3	3,6-dihydroxyflavoneIBA 09/2017 - 06/2015
2	Pregnenolone Carbonitrile (PCN)IBA 01/2020 - 01/2017
2	Virulence Factors (Pathogenicity Factors)IBA 01/2020 - 01/2017
2	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 01/2017
2	PyocyanineIBA 01/2020 - 01/2017
2	Nuclear Proteins (Protein, Nuclear)IBA 01/2019 - 01/2017
2	AntioxidantsIBA 12/2017 - 01/2013
2	Histone Deacetylases (Histone Deacetylase)IBA 10/2017 - 10/2012
2	DNA (Deoxyribonucleic Acid)IBA 09/2017 - 05/2016
2	Biomarkers (Surrogate Marker)IBA 09/2015 - 10/2012
2	Histones (Histone)IBA 06/2015 - 10/2012
1	Factor VIII (Coagulation Factor VIII)IBA 01/2022
1	Fetal Proteins (Fetoprotein)IBA 11/2021
1	Glycyrrhizic Acid (Glycyrrhizin)IBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	grazoprevirIBA 01/2020
1	elbasvirIBA 01/2020
1	Peroxynitrous Acid (Peroxynitrite)IBA 01/2020
1	phenazine FDA Link 01/2020
1	dicarboxydine (DCD)IBA 01/2020
1	Free RadicalsIBA 01/2020
1	Peptides (Polypeptides)IBA 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2018
1	Fas Ligand Protein (Fas Ligand)IBA 11/2018
1	Phosphotransferases (Kinase)IBA 11/2018
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 11/2018
1	CalciumIBA 11/2018
1	MicellesIBA 12/2017
1	CurcuminIBA 12/2017
1	methoxy poly(ethylene glycol)-poly(lactide)IBA 12/2017
1	SolutionsIBA 12/2017
1	Histone Deacetylase 1IBA 10/2017
1	Tyrosine Kinase InhibitorsIBA 09/2017
1	Small Interfering RNA (siRNA)IBA 09/2017
1	MethyltransferasesIBA 09/2017
1	CarcinogensIBA 09/2017
1	Bacterial ToxinsIBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	Anti-Bacterial Agents (Antibiotics)IBA 06/2016
1	Presenilin-1IBA 01/2016
1	asaroneIBA 01/2016
1	vasectrin I (VS I)IBA 09/2015
1	SurvivinIBA 09/2015
1	Adrenergic Receptors (Adrenergic Receptor)IBA 05/2013
1	5-HT1A Serotonin ReceptorIBA 05/2013
1	LigandsIBA 05/2013
1	EquolIBA 01/2013

Therapy/Procedure

3	Liver Transplantation 01/2022 - 01/2020
2	Therapeutics 01/2017 - 01/2014
1	Blood Transfusion (Blood Transfusions) 03/2021
1	Orthopedic Procedures 03/2021
1	Acupressure (Shiatsu) 01/2021
1	Renal Dialysis (Hemodialysis) 01/2021
1	Aftercare (After-Treatment) 01/2020
1	Intravenous Injections 01/2019